Hypouricemic and xanthine oxidase inhibitory activities of the fractions of Coccinia grandis L. Voigt
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چکیده
منابع مشابه
In vitro antioxidant activities of the fractions of Coccinia grandis L. leaf extract.
The present study was aimed at investigating the antioxidant activities of the various fractions of the hydromethanolic extract of the leaves of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activities of the fractions have been evaluated by using nine in vitro assays and were compared to standard antioxidants such as ascorbic acid, alpha-tocopherol, curcumin and butylated hydroxy...
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In visceral leishmaniasis (VL), development of alternative safe therapeutic strategy is gaining paramount wherein natural components of plant origin have prominence. We explored Coccinia grandis (L.) Voigt, a medicinal plant known in traditional folk medicine, for its antileishmanial efficacy. SDS-PAGE analysis of the C. grandis leaf extract (Cg-Ex) showed few protein bands about 14-66 kDa amon...
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Antimicrobial activity of protease inhibitor isolated from Coccinia grandis (L.) Voigt. has been reported. A 14.3 kDa protease inhibitor (PI) was isolated and purified to homogeneity by ammonium sulfate precipitation (20-85% saturation), sephadex G-75, DEAE sepharose column and trypsin-sepharose affinity chromatography from the leaves of C. grandis. The purity was checked by reverse phase high ...
متن کاملProtease Inhibitors from Coccinia Grandis (l.) Voigt. Leaves: Purification, Characterization and Kinetic Properties
Cucurbits are rich source of protease inhibitors. A protein of 14.3 kDa designated as Coccinia grandis protease inhibitors (CGPI) was isolated from leaves of Coccinia grandis and purified to homogeneity by ammonium sulfate precipitation, Sephadex G-75 column, DEAE Sepharose column and TrypsinSepharose affinity chromatography. The purity was checked by reversed phase chromatography. The molecula...
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Flavonoids could serve as potent inhibitors of xanthine oxidase (XO). In the present study, the effects of Ruta graveolens L. extract and its major isolated flavonoids, quercetin and rutin, on guinea pig liver XO have been investigated. The inhibitory effects of R. graveolens, quercetin and its glycoside form, rutin, were assayed spectrophotometrically. R. graveolens...
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ژورنال
عنوان ژورنال: Oriental Pharmacy and Experimental Medicine
سال: 2008
ISSN: 1598-2386
DOI: 10.3742/opem.2008.7.5.477